Mela B3 Serum
Reviewed by SerumTruth Editorial · Updated July 2026
A pharmacy pigment serum whose disclosed 10% niacinamide is the sure thing and whose headline Melasyl is the part you take on trust. Gentle and well-tolerated for the appearance of an even tone, it is priced for the new molecule as much as the niacinamide.
- Evidence21 / 30
Strength of the research behind the key actives
- Niacinamide: moderate evidence
- Score is the average of the key actives’ evidence grades.
- Potency25 / 25
Dosed at studied levels, not fairy-dusted
- Niacinamide (10%): dosed at a clinical, high-end level for its category
- Potency tracks how strongly the actives are dosed, led by the strongest, not how many there are.
- Delivery & stability14 / 20
Delivery tech + packaging that protects fragile actives
- Delivery: standard
- Packaging: tinted glass
- No fragile actives here, so packaging barely moves the score.
- Formulation6 / 10
Disclosure, active breadth, and ingredient generation
- 1 of 1 actives disclose a concentration
- 1 key active (breadth credit caps at 3)
- No current-generation or synergy bonus
- Value10 / 15
What a month of use costs vs. the category
- About $27 per month to use
- $45 for 30 ml, used about twice a day (about 0.3 ml each time), so a bottle lasts about 1.7 months
- Band: $6/month or less earns full marks, $60/month or more hits the floor.
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What’s inside
| Active | Disclosed | Dose |
|---|---|---|
| Niacinamide | 10% | Clinical |
10% niacinamide, disclosed, paired with Melasyl, a proprietary molecule pitched as a melanin trapper for the appearance of dark spots, in an opaque dropper bottle. The niacinamide is the familiar, well-evidenced part; Melasyl is new and its support is largely brand-led so far. Niacinamide is not fragile, so packaging is not the story.
How it’s delivered
Air- and light-sensitive actives (vitamin C, copper peptides) lose potency fast in the wrong packaging, so delivery and the bottle are scored, not just what’s on the label.
The actives, explained
Cosmetic information for general education, not medical advice. The SerumProof score reflects our reading of publicly available research and formulation disclosures. See how scoring works.