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Dicarboxylic acid

Azelaic Acid

INCI: Azelaic Acid·Studied at 10% (cosmetic)·Moderate evidence

A dicarboxylic acid found naturally in grains such as wheat, rye and barley, used in cosmetic-strength formulas for the appearance of a clearer, more even-looking complexion. It is well tolerated relative to many other acids and is often reached for by people who find retinoids or stronger exfoliants too reactive on their skin. The higher-strength versions used for certain skin conditions are prescription drugs rather than cosmetics, so cosmetic azelaic acid is a distinctly different, gentler product.

Studied for

  • ·The appearance of an even, clearer-looking complexion
  • ·The look of a more refined, calm-looking surface
  • ·Support for the visible look of skin after blemishes fade
  • ·The appearance of reduced visible redness in reactive-looking skin

How it’s thought to work

Studied for association with the appearance of a more even complexion, thought to relate to azelaic acid’s effect on the visible look of pigment-producing activity and surface cell turnover. Cosmetic formulas sit around 10%, well below the prescription strengths used for medical purposes, and it is fairly stable on the shelf compared with many other acids. It is generally considered gentler than stronger exfoliating acids, which is part of why it is often recommended for reactive or sensitive-looking skin.

Landmark study· studied at 20%

A 20% azelaic acid cream was linked to visibly fewer blemishes on blemish-prone skin over 2 months versus a non-active cream.

Clinical and laboratory studies on treatment with 20% azelaic acid cream for acne. Acta Dermato-Venereologica Supplementum, 1989.

View on PubMed (PMID 2528256) ↗

Questions

Is a 10% azelaic serum the same as prescription azelaic acid?
No. Cosmetic suspensions around 10% are formulated for the appearance of an even, clear-looking complexion. Prescription azelaic acid is a higher-strength drug with different, regulated uses. It is a separate product entirely.
Can azelaic acid help with the look of redness?
It is studied for association with a calmer-looking, more even complexion, which is why it turns up in formulas aimed at visible redness as well as ones aimed at tone. Results are gradual and consistency matters more than strength.
Is azelaic acid gentle enough for sensitive skin?
It has a reputation as one of the better-tolerated acids and is a common alternative for people who react to retinoids or stronger exfoliants. As with any active, patch testing first is still a sensible approach.

Serums we’ve scored with Azelaic Acid

References

This dossier covers the efficacy evidence. For the safety and concern profile of Azelaic Acid, see PlainBody ↗, our sister site.