Heartleaf 80% Moisture Soothing Ampoule
Reviewed by SerumTruth Editorial · Price and formula checked July 2026
A cheap, likeable soothing ampoule that leans on a big dose of heartleaf with panthenol for backup. The heartleaf evidence is limited, so read it as a calming comfort layer rather than a treatment. For the price and the feel, it is an easy add.
- Evidence17 / 30
Strength of the research behind the key actives
- Heartleaf (Houttuynia Cordata): limited evidence
- Panthenol: moderate evidence
The average of the key actives’ evidence grades.
- Potency21 / 25
Dosed at studied levels, not fairy-dusted
- Heartleaf (Houttuynia Cordata) (80%): dosed at a studied level
- Panthenol: dosed at a studied level
How strongly the actives are dosed, led by the strongest, not how many there are.
- Delivery & stability14 / 20
Delivery tech + packaging that protects fragile actives
- Delivery: standard
- Packaging: clear dropper
- No fragile actives here, so packaging barely moves the score.
Delivery tech plus packaging, and packaging only counts when actives are fragile.
- Formulation5 / 10
Disclosure, active breadth, and ingredient generation
- 1 of 2 actives disclose a concentration
- 2 key actives (breadth credit caps at 3)
- Current-generation or synergistic: Heartleaf (Houttuynia Cordata)
Disclosure, active breadth, and current-generation or synergistic actives.
- Value13 / 15
What a month of use costs vs. the category
- About $15 per month to use
- $25 for 30 ml, used about twice a day (about 0.3 ml each time), so a bottle lasts about 1.7 months
What a month of use costs: full marks at $6 a month or less, the floor at $60 a month or more.
Tap any row to see how its score was built.
Ranks #54 of 84 hydration & barrier serums we have scored.
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What’s inside
| Active | Disclosed | Dose |
|---|---|---|
| Heartleaf (Houttuynia Cordata) | 80% | Studied |
| Panthenol | n/a | Studied |
An 80% heartleaf (houttuynia cordata) ampoule with panthenol, sodium hyaluronate and betaine for hydration, in a frosted glass dropper. It is a soothing, comfort-focused layer aimed at the appearance of a calmer, less-reddened complexion, close in spirit to a centella serum but built on heartleaf. Neither active is fragile.
How it’s delivered
Air- and light-sensitive actives (vitamin C, copper peptides) lose potency fast in the wrong packaging, so delivery and the bottle are scored, not just what’s on the label.
The actives, explained
What the research says
In lab testing on skin cells, heartleaf extract raised levels of filaggrin, a protein tied to a smoother, better hydrated skin barrier.
Antioxidant Houttuynia cordata extract upregulates filaggrin expression in an aryl hydrocarbon-dependent manner. Fukuoka Igaku Zasshi, 2014. PubMed ↗
In a placebo controlled trial, seven days of topical dexpanthenol was linked with more hydrated looking skin and a steadier looking skin barrier.
Effect of topically applied dexpanthenol on epidermal barrier function and stratum corneum hydration. Results of a human in vivo study. Arzneimittelforschung, 2000. PubMed ↗
A study of the active, not this exact product. What matters for the score is whether this serum uses it at a comparable dose.
Higher-scoring alternatives
Same category, better SerumProof score. Worth a look before you buy.
Revision history
- July 11, 2026Price and formula rechecked
- July 10, 2026Review published
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Cosmetic information for general education, not medical advice. The SerumProof score reflects our reading of publicly available research and formulation disclosures. See how scoring works.