Hyalu B5 Serum
Reviewed by SerumTruth Editorial · Price and formula checked July 2026
A pharmacy-standard hydrator that does the comfort job well and is priced above the bargain HA serums for the finish and the brand. Be clear on what it is: the look of hydration and calm, not anti-aging. If you want a reliable, fuss-free hydrating layer, it delivers.
- No active concentrations are disclosed
- Evidence21 / 30
Strength of the research behind the key actives
- Hyaluronic Acid: moderate evidence
- Panthenol: moderate evidence
- Madecassoside: moderate evidence
The average of the key actives’ evidence grades.
- Potency20 / 25
Dosed at studied levels, not fairy-dusted
- Hyaluronic Acid: dosed at a studied level
- Panthenol: dosed at a studied level
- Madecassoside: present, but below a studied dose
How strongly the actives are dosed, led by the strongest, not how many there are.
- Delivery & stability14 / 20
Delivery tech + packaging that protects fragile actives
- Delivery: standard
- Packaging: tinted glass
- No fragile actives here, so packaging barely moves the score.
Delivery tech plus packaging, and packaging only counts when actives are fragile.
- Formulation4 / 10
Disclosure, active breadth, and ingredient generation
- 0 of 3 actives disclose a concentration
- 3 key actives (breadth credit caps at 3)
- Current-generation or synergistic: Panthenol, Madecassoside
Disclosure, active breadth, and current-generation or synergistic actives.
- Value11 / 15
What a month of use costs vs. the category
- About $24 per month to use
- $40 for 30 ml, used about twice a day (about 0.3 ml each time), so a bottle lasts about 1.7 months
What a month of use costs: full marks at $6 a month or less, the floor at $60 a month or more.
Tap any row to see how its score was built.
Ranks #53 of 84 hydration & barrier serums we have scored.
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What’s inside
| Active | Disclosed | Dose |
|---|---|---|
| Hyaluronic Acid | n/a | Studied |
| Panthenol | n/a | Studied |
| Madecassoside | n/a | Light |
Two molecular weights of hyaluronic acid with panthenol (vitamin B5) and a little madecassoside, in a tinted dropper bottle. It is a hydration and comfort serum aimed at the appearance of plumper, calmer-looking skin, not a tone or fine-line treatment. None of the actives are fragile, so packaging is not a concern here. It layers cleanly under moisturiser and sunscreen.
How it’s delivered
Air- and light-sensitive actives (vitamin C, copper peptides) lose potency fast in the wrong packaging, so delivery and the bottle are scored, not just what’s on the label.
The actives, explained
What the research says
A multicenter study linked a topical hyaluronic acid serum with better looking hydration, tone, and texture over several follow up visits.
Multicenter evaluation of a topical hyaluronic acid serum. Journal of Cosmetic Dermatology, 2022. PubMed ↗
In a placebo controlled trial, seven days of topical dexpanthenol was linked with more hydrated looking skin and a steadier looking skin barrier.
Effect of topically applied dexpanthenol on epidermal barrier function and stratum corneum hydration. Results of a human in vivo study. Arzneimittelforschung, 2000. PubMed ↗
A study of the active, not this exact product. What matters for the score is whether this serum uses it at a comparable dose.
Higher-scoring alternatives
Same category, better SerumProof score. Worth a look before you buy.
Revision history
- July 11, 2026Price and formula rechecked
- July 10, 2026Review published
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Cosmetic information for general education, not medical advice. The SerumProof score reflects our reading of publicly available research and formulation disclosures. See how scoring works.