Skip to content
La Roche-Posay

Retinol B3 Serum

$45·30 ml·~$14/mo to use

Reviewed by SerumTruth Editorial · Price and formula checked July 2026

A sensibly dosed, disclosed 0.3% retinol backed by niacinamide from a pharmacy brand that knows sensitive skin. The alcohol and fragrance keep it from being for everyone, but the transparency and price make it fair value.

What we like
  • Air- or light-sensitive actives in protective, opaque packaging
Watch-outs
  • 1 listed active is fairy-dusted below the 1% line
SerumProof score74 / 100
  • Evidence22 / 30

    Strength of the research behind the key actives

    • Retinol: strong evidence
    • Niacinamide: moderate evidence
    • Retinyl Palmitate: limited evidence

    The average of the key actives’ evidence grades.

  • Potency19 / 25

    Dosed at studied levels, not fairy-dusted

    • Retinol (0.3%): dosed at a studied level
    • Niacinamide: dosed at a studied level
    • Retinyl Palmitate: below the 1% line, treated as fairy-dusted

    How strongly the actives are dosed, led by the strongest, not how many there are.

  • Delivery & stability16 / 20

    Delivery tech + packaging that protects fragile actives

    • Delivery: standard
    • Packaging: airless, opaque
    • Air- or light-sensitive actives (Retinol, Retinyl Palmitate), so packaging is scored.

    Delivery tech plus packaging, and packaging only counts when actives are fragile.

  • Formulation4 / 10

    Disclosure, active breadth, and ingredient generation

    • 1 of 3 actives disclose a concentration
    • 3 key actives (breadth credit caps at 3)
    • No current-generation or synergy bonus

    Disclosure, active breadth, and current-generation or synergistic actives.

  • Value13 / 15

    What a month of use costs vs. the category

    • About $14 per month to use
    • $45 for 30 ml, used about once a day (about 0.3 ml each time), so a bottle lasts about 3.3 months
    • Frequency is set by Retinol, which is used no more than 7x a week, so a bottle stretches further

    What a month of use costs: full marks at $6 a month or less, the floor at $60 a month or more.

Tap any row to see how its score was built.

Ranks #22 of 25 retinoids serums we have scored.

Affiliate links. We may earn a commission at no cost to you. It never changes our score.

What’s inside

ActiveDisclosedDose
Retinol0.3%Studied
Niacinamiden/aStudied
Retinyl Palmitaten/aBelow 1% line

0.3% retinol (part pure, part gradual-release, disclosed as a total) with niacinamide high on the list and a trace of retinyl palmitate as a supporting ester, in an opaque pump. It is built around sensitive skin, though the formula does contain alcohol and fragrance, which reactive skin should note.

How it’s delivered

DeliveryStandardPackagingAirless, opaque

Air- and light-sensitive actives (vitamin C, copper peptides) lose potency fast in the wrong packaging, so delivery and the bottle are scored, not just what’s on the label.

The actives, explained

What the research says

A year of use was linked to fewer visible crow’s feet lines and a more even-looking skin tone versus vehicle in this trial.

One-year topical stabilized retinol treatment improves photodamaged skin in a double-blind, vehicle-controlled trial. Journal of Drugs in Dermatology, 2015. PubMed ↗

Topical 5% niacinamide was linked to more even looking skin tone, softer looking lines, and less visible blotchiness after 12 weeks.

Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 2005. PubMed ↗

A study of the active, not this exact product. What matters for the score is whether this serum uses it at a comparable dose.

Higher-scoring alternatives

Same category, better SerumProof score. Worth a look before you buy.

Revision history
  1. July 11, 2026
    Price and formula rechecked
  2. July 10, 2026
    Review published

Spot an error or a reformulation? Tell us and we will fix it.

Cosmetic information for general education, not medical advice. The SerumProof score reflects our reading of publicly available research and formulation disclosures. See how scoring works.