Regenerist Retinol 24 Night Serum
Reviewed by SerumTruth Editorial · Updated July 2026
A gentle, barrier-friendly drugstore retinoid built on retinyl propionate plus niacinamide rather than a straight retinol. Easy to use and cheap, but the ester and the low retinol mean the evidence and the potency are modest.
- Evidence22 / 30
Strength of the research behind the key actives
- Retinyl Propionate: limited evidence
- Niacinamide: moderate evidence
- Retinol: strong evidence
- Score is the average of the key actives’ evidence grades.
- Potency18 / 25
Dosed at studied levels, not fairy-dusted
- Retinyl Propionate: dosed at a studied level
- Niacinamide: present, but below a studied dose
- Retinol: below the 1% line, treated as fairy-dusted
- Potency tracks how strongly the actives are dosed, led by the strongest, not how many there are.
- Delivery & stability16 / 20
Delivery tech + packaging that protects fragile actives
- Delivery: standard
- Packaging: airless, opaque
- Air- or light-sensitive actives (Retinyl Propionate, Retinol), so packaging is scored.
- Formulation3 / 10
Disclosure, active breadth, and ingredient generation
- 0 of 3 actives disclose a concentration
- 3 key actives (breadth credit caps at 3)
- Current-generation or synergistic: Retinyl Propionate
- Value15 / 15
What a month of use costs vs. the category
- About $7 per month to use
- $29 for 38 ml, used about once a day (about 0.3 ml each time), so a bottle lasts about 4.2 months
- Frequency is set by Retinyl Propionate, which is used no more than 7x a week, so a bottle stretches further
- Band: $6/month or less earns full marks, $60/month or more hits the floor.
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What’s inside
| Active | Disclosed | Dose |
|---|---|---|
| Retinyl Propionate | n/a | Studied |
| Niacinamide | n/a | Light |
| Retinol | n/a | Below 1% line |
A vitamin B3 plus retinol complex: retinyl propionate as the main retinoid high on the list, with niacinamide, a little retinol and a peptide lower down, in an opaque pump. It is fragrance-free and gentle. Retinyl propionate is a milder ester that carries lighter evidence than retinol at a real dose.
How it’s delivered
Air- and light-sensitive actives (vitamin C, copper peptides) lose potency fast in the wrong packaging, so delivery and the bottle are scored, not just what’s on the label.
The actives, explained
Cosmetic information for general education, not medical advice. The SerumProof score reflects our reading of publicly available research and formulation disclosures. See how scoring works.