TNS Advanced+ Serum
Reviewed by SerumTruth Editorial · Price and formula checked July 2026
The packaging is excellent and the price matches it. The growth-factor evidence is real but modest and largely brand-led, and on proven actives per dollar it is very hard to justify over options a tenth of the cost. You are paying for the science story and the bottle.
- Air- or light-sensitive actives in protective, opaque packaging
- No active concentrations are disclosed
- Costly to use, about $187 a month
- Evidence17 / 30
Strength of the research behind the key actives
- Growth Factors (TNS): moderate evidence
- Trifluoroacetyl Tripeptide-2: limited evidence
The average of the key actives’ evidence grades.
- Potency20 / 25
Dosed at studied levels, not fairy-dusted
- Growth Factors (TNS): dosed at a studied level
- Trifluoroacetyl Tripeptide-2: present, but below a studied dose
How strongly the actives are dosed, led by the strongest, not how many there are.
- Delivery & stability16 / 20
Delivery tech + packaging that protects fragile actives
- Delivery: standard
- Packaging: airless, opaque
- Air- or light-sensitive actives (Growth Factors (TNS)), so packaging is scored.
Delivery tech plus packaging, and packaging only counts when actives are fragile.
- Formulation4 / 10
Disclosure, active breadth, and ingredient generation
- 0 of 2 actives disclose a concentration
- 2 key actives (breadth credit caps at 3)
- Current-generation or synergistic: Growth Factors (TNS), Trifluoroacetyl Tripeptide-2
Disclosure, active breadth, and current-generation or synergistic actives.
- Value3 / 15
What a month of use costs vs. the category
- About $187 per month to use
- $295 for 28.4 ml, used about twice a day (about 0.3 ml each time), so a bottle lasts about 1.6 months
What a month of use costs: full marks at $6 a month or less, the floor at $60 a month or more.
Tap any row to see how its score was built.
Ranks #9 of 15 peptides serums we have scored.
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What’s inside
| Active | Disclosed | Dose |
|---|---|---|
| Growth Factors (TNS) | n/a | Studied |
| Trifluoroacetyl Tripeptide-2 | n/a | Light |
A prestige growth-factor serum built on Human Fibroblast Conditioned Media, plus whey peptides and a supporting peptide and antioxidant blend, in an airless, opaque, dual-chamber pump. The packaging protects its fragile proteins the way this category should. Levels are proprietary and not disclosed.
How it’s delivered
Air- and light-sensitive actives (vitamin C, copper peptides) lose potency fast in the wrong packaging, so delivery and the bottle are scored, not just what’s on the label.
The actives, explained
What the research says
In a pilot study, twice-daily topical growth factor gel was linked to smoother-looking skin and fewer visible fine lines after 60 days.
Reversal of photodamage with topical growth factors: a pilot study. Journal of Cosmetic Laser Therapy, 2003. PubMed ↗
A study of the active, not this exact product. What matters for the score is whether this serum uses it at a comparable dose.
Higher-scoring alternatives
Same category, better SerumProof score. Worth a look before you buy.
Revision history
- July 11, 2026Price and formula rechecked
- July 10, 2026Review published
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Cosmetic information for general education, not medical advice. The SerumProof score reflects our reading of publicly available research and formulation disclosures. See how scoring works.