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Manyo

Bifida Cica Herb Serum

$25·50 ml·~$9/mo to use

Reviewed by SerumTruth Editorial · Updated July 2026

A well-disclosed calming serum: 42% centella extract and 35% bifida ferment lysate are both genuinely high, named doses, not a fairy-dusted herb story. The twelve-herb blend and niacinamide are real but secondary, undisclosed additions, and the closing lavender oil is a mild fragrance-allergen note for sensitive skin. For the centella-and-ferment combination alone, this is an honest, fairly priced pick.

SerumProof score77 / 100
  • Evidence21 / 30

    Strength of the research behind the key actives

    • Centella Asiatica (Cica): moderate evidence
    • Bifida Ferment Lysate: moderate evidence
    • Niacinamide: moderate evidence

    The average of the key actives’ evidence grades.

  • Potency21 / 25

    Dosed at studied levels, not fairy-dusted

    • Centella Asiatica (Cica) (42%): dosed at a studied level
    • Bifida Ferment Lysate (35%): dosed at a studied level
    • Niacinamide: dosed at a studied level

    How strongly the actives are dosed, led by the strongest, not how many there are.

  • Delivery & stability14 / 20

    Delivery tech + packaging that protects fragile actives

    • Delivery: standard
    • Packaging: tinted glass
    • No fragile actives here, so packaging barely moves the score.

    Delivery tech plus packaging, and packaging only counts when actives are fragile.

  • Formulation7 / 10

    Disclosure, active breadth, and ingredient generation

    • 2 of 3 actives disclose a concentration
    • 3 key actives (breadth credit caps at 3)
    • Current-generation or synergistic: Bifida Ferment Lysate

    Disclosure, active breadth, and current-generation or synergistic actives.

  • Value14 / 15

    What a month of use costs vs. the category

    • About $9 per month to use
    • $25 for 50 ml, used about twice a day (about 0.3 ml each time), so a bottle lasts about 2.8 months

    What a month of use costs: full marks at $6 a month or less, the floor at $60 a month or more.

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What’s inside

ActiveDisclosedDose
Centella Asiatica (Cica)42%Studied
Bifida Ferment Lysate35%Studied
Niacinamiden/aStudied

A two-active herbal serum led by a disclosed 42% Centella Asiatica extract and 35% Bifida Ferment Lysate (77% combined), with niacinamide sitting just above the 1,2-hexanediol preservative line at an undisclosed level, and a supporting blend the brand markets as twelve herbs, tea tree leaf water, eggplant fruit, rooibos (Aspalathus Linearis), oregano, basil, olive leaf, coriander, lavender, melissa, rosemary, ivy gourd and thyme extracts among them, in a tinted green glass dropper bottle. A small amount of lavender oil, with its linalool and limonene, closes out the list, worth a patch test for fragrance-reactive skin. Neither centella nor the bifida ferment is fragile, so the tint is a comfort choice here rather than a necessity.

How it’s delivered

DeliveryStandardPackagingTinted glass

Air- and light-sensitive actives (vitamin C, copper peptides) lose potency fast in the wrong packaging, so delivery and the bottle are scored, not just what’s on the label.

The actives, explained

Cosmetic information for general education, not medical advice. The SerumProof score reflects our reading of publicly available research and formulation disclosures. See how scoring works.