Skip to content
Manyo

Bifida Cica Herb Serum

$25·50 ml·~$9/mo to use

Reviewed by SerumTruth Editorial · Price and formula checked July 2026

A well-disclosed calming serum: 42% centella extract and 35% bifida ferment lysate are both genuinely high, named doses, not a fairy-dusted herb story. The twelve-herb blend and niacinamide are real but secondary, undisclosed additions, and the closing lavender oil is a mild fragrance-allergen note for sensitive skin. For the centella-and-ferment combination alone, this is an honest, fairly priced pick.

What we like
  • Cheap to use, about $9 a month
SerumProof score77 / 100
  • Evidence21 / 30

    Strength of the research behind the key actives

    • Centella Asiatica (Cica): moderate evidence
    • Bifida Ferment Lysate: moderate evidence
    • Niacinamide: moderate evidence

    The average of the key actives’ evidence grades.

  • Potency21 / 25

    Dosed at studied levels, not fairy-dusted

    • Centella Asiatica (Cica) (42%): dosed at a studied level
    • Bifida Ferment Lysate (35%): dosed at a studied level
    • Niacinamide: dosed at a studied level

    How strongly the actives are dosed, led by the strongest, not how many there are.

  • Delivery & stability14 / 20

    Delivery tech + packaging that protects fragile actives

    • Delivery: standard
    • Packaging: tinted glass
    • No fragile actives here, so packaging barely moves the score.

    Delivery tech plus packaging, and packaging only counts when actives are fragile.

  • Formulation7 / 10

    Disclosure, active breadth, and ingredient generation

    • 2 of 3 actives disclose a concentration
    • 3 key actives (breadth credit caps at 3)
    • Current-generation or synergistic: Bifida Ferment Lysate

    Disclosure, active breadth, and current-generation or synergistic actives.

  • Value14 / 15

    What a month of use costs vs. the category

    • About $9 per month to use
    • $25 for 50 ml, used about twice a day (about 0.3 ml each time), so a bottle lasts about 2.8 months

    What a month of use costs: full marks at $6 a month or less, the floor at $60 a month or more.

Tap any row to see how its score was built.

Ranks #20 of 84 hydration & barrier serums we have scored.

Affiliate links. We may earn a commission at no cost to you. It never changes our score.

What’s inside

ActiveDisclosedDose
Centella Asiatica (Cica)42%Studied
Bifida Ferment Lysate35%Studied
Niacinamiden/aStudied

A two-active herbal serum led by a disclosed 42% Centella Asiatica extract and 35% Bifida Ferment Lysate (77% combined), with niacinamide sitting just above the 1,2-hexanediol preservative line at an undisclosed level, and a supporting blend the brand markets as twelve herbs, tea tree leaf water, eggplant fruit, rooibos (Aspalathus Linearis), oregano, basil, olive leaf, coriander, lavender, melissa, rosemary, ivy gourd and thyme extracts among them, in a tinted green glass dropper bottle. A small amount of lavender oil, with its linalool and limonene, closes out the list, worth a patch test for fragrance-reactive skin. Neither centella nor the bifida ferment is fragile, so the tint is a comfort choice here rather than a necessity.

How it’s delivered

DeliveryStandardPackagingTinted glass

Air- and light-sensitive actives (vitamin C, copper peptides) lose potency fast in the wrong packaging, so delivery and the bottle are scored, not just what’s on the label.

The actives, explained

What the research says

In a controlled trial, a Centella asiatica cream was linked with a better looking, more even scar appearance over 12 weeks.

A Prospective Randomized, Controlled, Double-Blind Trial of the Efficacy Using Centella Cream for Scar Improvement. Evidence-Based Complementary and Alternative Medicine, 2018. PubMed ↗

Lab testing on skin cells found bifida ferment lysate boosted skin barrier related genes and showed antioxidant activity.

The pivotal role of Bifida Ferment Lysate on reinforcing the skin barrier function and maintaining homeostasis of skin defenses in vitro. Journal of Cosmetic Dermatology, 2023. PubMed ↗

A study of the active, not this exact product. What matters for the score is whether this serum uses it at a comparable dose.

Higher-scoring alternatives

Same category, better SerumProof score. Worth a look before you buy.

Revision history
  1. July 11, 2026
    Price and formula rechecked
  2. July 10, 2026
    Review published

Spot an error or a reformulation? Tell us and we will fix it.

Cosmetic information for general education, not medical advice. The SerumProof score reflects our reading of publicly available research and formulation disclosures. See how scoring works.