Multi-Peptide + HA Serum
Reviewed by SerumTruth Editorial · Price and formula checked July 2026
A broad peptide serum for around fifteen dollars, with hydration built in. The catch is disclosure: none of the peptide levels are stated, so you take the doses on trust. As a low-cost, low-risk entry into peptides, it is still good value.
- Cheap to use, about $12 a month
- No active concentrations are disclosed
- Evidence18 / 30
Strength of the research behind the key actives
- Matrixyl 3000: moderate evidence
- Matrixyl Synthe'6: limited evidence
- Hyaluronic Acid: moderate evidence
The average of the key actives’ evidence grades.
- Potency21 / 25
Dosed at studied levels, not fairy-dusted
- Matrixyl 3000: dosed at a studied level
- Matrixyl Synthe'6: dosed at a studied level
- Hyaluronic Acid: dosed at a studied level
How strongly the actives are dosed, led by the strongest, not how many there are.
- Delivery & stability14 / 20
Delivery tech + packaging that protects fragile actives
- Delivery: standard
- Packaging: clear dropper
- No fragile actives here, so packaging barely moves the score.
Delivery tech plus packaging, and packaging only counts when actives are fragile.
- Formulation4 / 10
Disclosure, active breadth, and ingredient generation
- 0 of 3 actives disclose a concentration
- 3 key actives (breadth credit caps at 3)
- Current-generation or synergistic: Matrixyl 3000, Matrixyl Synthe'6
Disclosure, active breadth, and current-generation or synergistic actives.
- Value14 / 15
What a month of use costs vs. the category
- About $12 per month to use
- $19.9 for 30 ml, used about twice a day (about 0.3 ml each time), so a bottle lasts about 1.7 months
What a month of use costs: full marks at $6 a month or less, the floor at $60 a month or more.
Tap any row to see how its score was built.
Ranks #4 of 15 peptides serums we have scored.
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What’s inside
| Active | Disclosed | Dose |
|---|---|---|
| Matrixyl 3000 | n/a | Studied |
| Matrixyl Synthe'6 | n/a | Studied |
| Hyaluronic Acid | n/a | Studied |
The serum formerly sold as "Buffet": a broad stack of trademarked peptides (Matrixyl 3000, Matrixyl Synthe’6 and others) over multiple weights of hyaluronic acid, in a clear glass dropper. The peptides are the pitch, though The Ordinary does not disclose any of their levels, which is the transparency gap here. The peptides are not especially air-sensitive, so the clear dropper is a minor issue.
How it’s delivered
Air- and light-sensitive actives (vitamin C, copper peptides) lose potency fast in the wrong packaging, so delivery and the bottle are scored, not just what’s on the label.
The actives, explained
What the research says
In a 12-week trial, palmitoyl pentapeptide reduced the look of fine lines and wrinkles compared with a placebo cream in women with photoaged skin.
Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin. International Journal of Cosmetic Science, 2005. PubMed ↗
A multicenter study linked a topical hyaluronic acid serum with better looking hydration, tone, and texture over several follow up visits.
Multicenter evaluation of a topical hyaluronic acid serum. Journal of Cosmetic Dermatology, 2022. PubMed ↗
A study of the active, not this exact product. What matters for the score is whether this serum uses it at a comparable dose.
Higher-scoring alternatives
Same category, better SerumProof score. Worth a look before you buy.
Revision history
- July 11, 2026Price and formula rechecked
- July 10, 2026Review published
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Cosmetic information for general education, not medical advice. The SerumProof score reflects our reading of publicly available research and formulation disclosures. See how scoring works.